Optimal Treatment Strategies for use of Anti-Obesity Medications (AOMs) in Children and Adolescents Research Coordinating Center (U24 Clinical Trial Not Allowed)
National Institutes of Health · Diabetes, Digestive, and Kidney Diseases Extramural Research (93.847)
Posted 8 Jun 2026 · 8 days left
In plain terms
The US National Institutes of Health funds a Research Coordinating Center to lead a consortium testing anti-obesity medication strategies in children and adolescents, evaluating optimal timing, dosing, and adjunct therapies. Only US-based organisations including non-profits, universities, businesses, and government agencies may apply, with applications due by 9 October 2026.
A generated summary of the donor's text; the original wording is below.
Summary
This Notice of Funding Opportunity (NOFO) invites applications for a Research Coordinating Center (RCC) to participate in a consortium of clinical centers that will test anti-obesity medication (AOM) treatment strategies for youth with obesity that maximize benefits and minimize risks of AOM use. Such intervention strategies should support the promotion of healthy growth and development; adequate nutritional status/intake, healthy eating and physical activity behaviors; mental health and well-being (e.g., body image, self-esteem, mood, etc.), and quality of life and be feasible to implement in clinical care settings. Priority areas include testing strategies to determine optimal developmental stage for AOM initiation, rate and amount of weight loss, AOM class, dose, frequency, and duration, and content and intensity of adjunct lifestyle therapies that may be imperative to ensure normal psychological and physical development and to potentially avoid lifelong dependence on AOMs. Investigators should also evaluate potential predictors of response/ nonresponse to various treatment strategies under evaluation. The clinical centers may conduct independent or multicenter trials but will…
Excerpt from the donor's page. The full text, annexes and forms are on the original call.
Who can apply
- NGO / civil society
- Academic or research institution
- Private company
- Government body
- Community-based organisation
Eligibility and conditions
Show the eligibility text from the source
Applicant types: County governments; Special district governments; City or township governments; For profit organizations other than small businesses; State governments; Native American tribal governments (Federally recognized); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; Native American tribal organizations (other than Federally recognized tribal governments); Small businesses; Public housing authorities/Indian housing authorities; Private institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Public and State controlled institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.